INTERNAL QUALITY CONTROL APPLIED TO CENMAST, A PRODUCT TO DETECT MASTITIS

[摘要] CENMAST is a diagnostic test similar to the California Mastitis Test (CMT). During the production process at Centro Nacional de Sanidad Agropecuaria (CENSA), the Quality control Laboratory tests the specifications of the product, determining the active substance, pH and density, the results are under Internal Quality Control Program. A batch was evaluated as a working reference material, to be used as a sample of quality control, also it was used for the validation of the assay precision under repeatability conditions and intermediate conditions changing the analysts, working days, equipments and calibration. A suitable precision among replicas was obtained and critical ranges of 0,03, 0,30, 0,006 were reported for the active substance, pH and density respectively. The distribution of the control sample values plotted on the control graphics demonstrated that the analytical methods are under statistic control. The quality internal control demonstrated the reliability of the results in control and product samples when evaluated in parallel.

[学科分类] 兽医学

[关键词] internal quality control; mastitis; diagnosisINTRODUCCIÓNLa mastitis es considerada como la enfermedad más importante de la lechería a nivel mundial;provoca grandes pérdidas en la producción láctea fundamentalmente en su forma subclínica