This paper aimedto evaluate the effect of inclusion of cassava leaf protein concentrate (CLPC)in Nile tilapia diets during sex reversal phase. During the experiment, whichlasted for 28 days, 300 tilapia larvae at 7 days of age were distributed into20 aquarium tanks with 30 L of water capacity in a complete randomized design,with 5 levels of cassava leaf protein concentrate (0; 5; 10; 15; and 20%), eachone with four replicates. One aquarium with 15 larvae was considered the experimentalunit. The five rations were iso-proteic and iso-energetic containing 38.6% ofdigestible protein and 3,300 kcal of DE/kg diet. The average values of temperature,pH, dissolved oxygen and electric conductivity of the water in the experimentalaquarium were 23.90 ± 1.35ºC; 7.23 ± 0.30; 5.15 ± 0.84mg/L; and 105.91 ± 4.73 μS/cm,respectively. At the end of the experiment, no significant differences wereobserved on the weight, final length, weight gain and survival rate of the larvaethat were fed cassava leaf protein concentrate. The use of cassava leaf proteinconcentrate at levels up to 20% in the diets for Nile tilapia in sex reversalphase do not harm the survival neither the performance of the animals.