Two experimentswere carried out with the objective to determine the effect of replacing cornby dried citrus pulp and wet brewer grain on apparent digestibility of nutrientsof the diet, ruminal parameters and performance of sheep. The diets were definedby the replacement of corn (control) by dried citrus pulp or by a mixture ofwet brewer grain and citrus pulp. In experiment 1, for evaluation of intake,apparent digestibility of nutrients and ruminal parameters, 12 Santa Ines ramlambs fitted with canulas in the rumen were assigned to a randomized completeblock design with three diets and four replicates. In experiment two, for performanceevaluation, 48 ewe lambs were confined and fed the same diets of experiment1. Replacement of corn by dried citrus pulp did not affect intake or digestibilityof nutrients in the diet. However, the inclusion of wet brewer grain reducedintake and apparent digestibility of nutrients, with exception of NDF. Apparentdigestibility of NDF was similar among diets. Inclusion of wet brewer grainin the diet decreased ruminal concentration of acetate and propionate and increasedacetate/propionate ratio and ruminal pH. In general, there is no differencebetween the diet containing corn and that containing citrus pulp in total replacementto corn. The use of wet brewer grain, however, reduces average daily gain, finalbody weight and feed efficiency.