The trial was conductedto evaluate the performance and morphologic changes of gastrointestinal tractand economic analysis for broilers fed sorghum-soybean meal-based diets, supplementedor not with multienzymatic complex (xilanase, amylase, protease), in the starting(experiment I) and finishing (experiment II) phases. The experiment was analyzedas a randomized block design with a 3 x 2 factorial arrangement [three sorghumlevels (0, 50, and 100%) x enzyme level (0 and 100%)]. The experimental unitwas a box with 17 birds and eight replicates per treatment. In the experimentI (1 to 21 days), the sorghum-based diets did not affect feed intake, weightgain, and feed conversion. However, the increase of level sorghum decreasedgizzard weight and of enzyme increased jejunum and ileum weights. In the experimentII (22 to 42 days), the sorghum-based diets also did not affect broilers feedintake, weight gain, feed:gain ratio, and relative weights of duodenum, jejunum,ileum and caecum. Increasing enzyme levels decreased significantly carcass yieldand increased weights pf proventriculus, gizzard and pancreas. Based on theeconomic analysis, it is suggested the corn replacement with sorghum of 50%for starting and finishing broilers.