Increased prevalence of hyperthyroidism as an early and transient side-effect of implementing iodine prophylaxis

[摘要] ObjectiveTo assess the prevalence of hyperthyroidism just after implementation of iodine prophylaxis among adults from an area with iodine deficiency.Study design and subjectsA total of 1648 adults (age 16 years and older) were sampled from an area of southern Poland during two nationwide epidemiological surveys. Of these, 1424 adults with negative medical history for thyroid disorders qualified for final analysis. The authors compared thyroid dysfunction in participants prior to (1989–1990) and after implementation of iodine prophylaxis (1997–1999).SettingThe southern part of Poland.ResultsWe found an increase in the serum concentration of anti-thyroid microsomal antibodies from 4.9% in the years 1989–1990 to 12.1% after introduction of iodised household salt (P 

[学科分类] 卫生学

[关键词] Iodine deficiency;Iodine prophylaxis;Iodine-induced hyperthyroidism