The effect of salsola tuberculatiformis bostchantzev on the androgen and glucocorticoid receptors in prostate cancer cell lines

[摘要] ENGLISH ABSTRACT: This study describes:1. The preparation of a biologically active methanol extract fromS.tuberculatiformis.2. The demonstration of biological activity for both the crudeS.tuberculatiformis extract and Compound A.3. The effects of the crude S.tuberculatiformis extract and Compound Aon nuclear translocation of the androgen and estrogens receptors inthree different prostate cancer cell-lines.4. Cell viability assays demonstrating the potency (IC50) for Compound Aand the crude S.tuberculatiformis extract between the three prostatecancer cell-lines.5. Caspase assays to demonstrate apoptosis for the crudeS.tuberculatiformis extract and Compound A in prostate cancer celllines.

[发布机构] Stellenbosch University