Aging is a dynamicprocess of morphological, functional, psychological and biochemical modificationsthat start at birth and develop throughout our lives. Getting old is not thesame as getting sick. Along the aging road, a series of changes in the organsand systems take place. In the aging process, the risk of acquiring diseasesand disabilities increases, as well as the need to lay down goals to improvethe older adult's health. Based on these concerns, we proposed to describe theoral changes occurring in older adults, and to determine the relationship betweensex and systemic alterations with the appearance of oral changes in the olderadult. A higher percentage of oral changes was found in the totally edentulousolder adults. The reabsorbed alveolar crest was the most frequent oral change.The greatest number of oral changes was reported in the females, and a directrelation was evidenced between the systemic alterations and the oral changes,among which the group of diabetic patients was the most affected.