原核ゲノムにおけるタンデムリピート検索のためのカラーコーディング法の評価

[摘要] References(22)Cited-By(1)By using the color-coding (CC) method, which is based on visual inspection by eyes, tandem repeats (TRs) were searched in the Yersinia pestis, Deinococcus radiodurans and Haemophilus influenzae genomes by three independent inspectors, and the detected TRs were compared to investigate the individual variations among inspectors in detecting TRs.We also compared the CC method with Tandem Repeats Finder (TRF) that is one of the algorithmic methods for searching TRs, in the detection ability of TRs, demonstrating that the CC method can get much larger number of TRs than TRF, even long TRs with much lower sequence identity.

[学科分类] 生物化学/生物物理

[关键词] tandem repeats;タンデムリピート;color-coding (CC);カラーコーディン�?(CC)法;visual inspection;視覚による検知;performance evaluation;性能評価;individual variationindividual variation;個人差;Tandem Repeats Finder (TRF)