Pemphigusis a bollous auto-immune disease. It's a rare disease, but potentially fatal.There are four clinical and pathological variants: pemphigus vulgaris, pemphigusvegetans, pemphigus foliaceus and pemphigus erythematosus. Through the histopathologicalexam, the common characteristic to all types of pemphigus is the acantholyse.It's reported a case of a pacient of 43 years old with anal and perineal blesseswitch final diagnosis was pemphigus vegetans, associated to HPV (Human PapillomaVirus), with literature review.
