Recurrence of HPV lesions after surgical treatment in HIV-positive patients

[摘要] HPV is the commonest anal disease in HIV-infected patients. In the present study we investigated the recurrence rates after surgical treatment of HPV in HIV-positive patients. A retrospective review was performed on 74 patients who underwent surgical intervention for medically intractable anal condyloma at Hospital Heliópolis, São Paulo, Brazil, from July 2004 to June 2007. The majority of the patients were male (91,9%), ranged in age from 22 to 57 years (mean 36 years). Viral load ranged from undetectable to 488.000 copies/mm3, T CD4 cells counts from 19 to 900 cells/mm3. We observed high grade anal squamous intraepithelial lesions in 12,2% and anal condyloma recurred in 58,1%. A significantly lower recurrence was observed in patients with T CD4 cells counts =200 cells/mm3 and viral load undetectable.

[学科分类] 心脏病和心血管学

[关键词] Anal HPV;Anal wart;AIDS;Recurrence;Anal dysplasia