Molecular biology studies are presently regardedas a major source for research in Medicine, and an increasing number of medicalprofessionals are interested in improving their knowledge and scientific productionin this subject. However, structuring the research project may become a difficultchallenge due to the wide range of methods and techniques available in thisarea, most of them depending on existing technological facilities and personalskill. The aim of this study is to contribute for the task of setting up a researchproject by presenting a brief review of most used structure models in molecularbiology studies as well as its related principles and methods.