Thepurpose of this study is to analyze the results found in the pathological examinationand PCR test for clinical and subclinical HPV anal infections in four groupsof patients. Methods: The four groups studied were: ten patients with idiopathicanal pruritus, six with treated HPV genital infection, six with treated analcondyloma, and eight with anal condyloma. Eight patients with condyloma underwentwart biopsy, and high-resolution anoscopy with directed biopsy was performedin the remaining 22 patients. Paraffin wax embedded biopsy specimens were sentto pathological analysis, and later PCR was carried out on the same samples.Results: Through the pathological examination, the presence of HPV is positivein all patients studied: clinically in the eight patients with condyloma, andsubclinically in the others 22. Thirteen of these 22 patients presented andassociated intraepithelial neoplasia. PCR was positive in 91,9% of the 22 patientsthose who presented the subclinical infection at pathology examination and 87,5%of the eight patients that presented the clinical infection the most commontype of anal subclinical HPV infection was HPV-16 and HPV-11 when warts werepresented. Conclusions: Pathological findings related to HPV were presentedin all patients studied, and 13 cases were diagnosed two of them were carcinomain situ. PCR was positive in 91,9% of patients presenting the subclinicalinfection, and in 87,5% with the clinical infection was HPV-16, and for wartsHPV-11.
