Malignant tumorsof the anal canal and anus are rare pathologic events, representing less than2% of all tumors of the colon, rectum and anus; according to reports, the incidenceof melanoma does not achieve 0,1 to 1,2% of malignant tumors. Authors describetwo cases of melanoma, discussing the data described in literature, focusingon the diagnosis aspects, treatment, evolution and prognosis. Cure rates arelow and the disease presents high rates of mortality in short term.