The inclusion ofthe theme - anal cancer - in this revision, in spite of its relative rarity,it answers, partly, to the purpose of calling attention for the significantincrease of that lesion and its narrow relationship with sexually transmissiblediseases mainly caused by the human papilloma virus (HPV); its nosologic aspects,epidemiology, etiology, and the multifactorial nature of risk that is associatedto the disease, its prevention, and, partly, to reveal the current definitionof the treatment.