Colon lauderingis used in many colon surgeries. The LIATO, that promotes cleanness of colon,demonstrates an increase of the surgical time and increase risk of infection.This study compares colonic anastomosis with and without preparation, throughhistomorfometric analysis. 30 rabbits were submitted to the surgery treatmentand had been evaluated and divided in groups: group 1 (control) and group 2(LIATO). Carried through statistical study with the program Prism® 4 forp< 5%. The analisis found acute inflammatory infiltrated with discrete biggeraverage in the anastomoses of group 2. Chronic inflammatory infiltrated withaverage of 1,9 in the anastomoses of group 2 and of 2,1 in the ones withoutpreparation. Necrosis in 15,7% in the LIATO against 13,5% in the group withoutpreparation. Calcium deposit in 43% of the anastomoses with preparation andin 30%, of the ones without preparation. Bigger colágen concentrationwere met in the anastomoses made with the intestinal laudering. Incidence ofinterlaced colagen fibres was observed in 86% of the anastomoses of the searchedone and in 70% in the control group. We conclude that the LIATO presents betterincidence of interlaced colagen fibres and fibre concentration resulting inbetter anastomosis.