INTRODUCTION:There is great prevalence of extra-intestinal manifestations (EIM) in Crohn'sdisease(CD) and ulcerative rectocolitis (UR), varying from 24 to 65%.
AIM: To determine the prevalence of EIM in UR and CD, establishing acorrelation with the diagnosis of the kind of intestinal inflammatory disease,extension, evolution time and disease activity.
METHODS: One thousand patients were evaluated at the Hospital das Clínicasda FMUSP, along the 1984 to 2004 period. Articular, dermatological, ophthalmologic,urologic, hepatic, pulmonary and vascular manifestations were studied.
RESULTS: 468 patients were studied with CD (46.8%) were studied and 532with UR (53.2%). 627 patients found (59.2% with UR and 66.7% with CD) with atleast one form of EIM. The average disease time of the EIM patients was of 10years. EIM were more frequent after the beginning of the intestinal symptoms.
CONCLUSIONS: Both in UR as in CD, the greater the extension of the diseasein the colon, the greater is the EIM incidence. Urologic manifestations weremore frequent in CD. Articular and dermatological manifestations were more prevalentin the feminine sex in both groups. Hepatic manifestations were more prevalentin CD. Articular, dermatological and vascular manifestations were related withthe activity of the intestinal disease in both groups.
