Condilomata acuminataand Schistosoma eggs are frequently found in the anal region, but thereis no report about the association of these diseases in this region. The associationof HPV infection and Schistosoma eggs in an HIV-positive patient wasfound in uterine cervix and there is evidence suggesting that this associationcan alters the natural history of these diseases. Like in the cervix, it ispossible that this interaction also occurs in the anal region. So, we reporta case of anal Condilomata acuminata, in an HIV-positive patient, that was ressectedand contained on histopathologic examination, multiple Schistosoma eggs.