Effect of the Rhizophora mangle L. bark preparation on the process of solid-liquid extraction

[摘要] Introduction: Rhizophora mangle L. bark, rich in tannin content, is the source of raw material for pharmaceuticals manufactured at the National Center for Animal and Plant Health (CENSA). For the extracts obtained from the bark to have the required quality, it is necessary that the bark be dried and grounded before lixiviation. Objectives: to evaluate different drying methods and several particle sizes on account of R. mangle aqueous extract yield. Methods: Three drying methods (oven, sun and shade) and 2 average bark particle sizes were used to evaluate the extract quality by determining the total soluble solid content, total tannins and in vitro antimicrobial activity. The Statgraphycs program was used to statistically compare the results. Results: it was observed that the oven drying and the sun drying were the most recommended methods; additionally, no significant differences were found in the extracts obtained from several average grounded bark particle sizes. Conclusions: the studied drying methods allowed achieving good results in the evaluation of the bark. The oven drying followed by the sun drying accounted for the shortest operating times.

[学科分类] 药理学