0068 Exogenous Heat Shock Protein 70 kDa Facilitates the Restoration of Sleep and Thermoregulatory Characteristics in Rat Endotoxemia Model

[摘要] IntroductionEndotoxemia is characterized by the sleep impairment and marked changes in thermoregulation and other physiological functions. The heat shock proteins 70 kDa (Hsp70) were shown to possess protective effects against numerous stress factors, including endotoxemia, in both in vitro and in vivo experiments. The purpose of the present study was to examine the effects of exogenous Hsp70/Hsc70 on sleep and thermoregulatory characteristics in rat endotoxemia model.

[学科分类] 生理学