Obstructive sleep apnea and longitudinal Alzheimer’s disease biomarker changes
[摘要] Study ObjectivesTo determine the effect of self-reported clinical diagnosis of obstructive sleep apnea (OSA) on longitudinal changes in brain amyloid PET and CSF biomarkers (Aβ42, T-tau, and P-tau) in cognitively normal (NL), mild cognitive impairment (MCI), and Alzheimer’s disease (AD) elderly.
[发布日期] [发布机构]
[效力级别] [学科分类] 生理学
[关键词] obstructive sleep apnea;Alzheimer’s disease;longitudinal study;CSF biomarkers;brain amyloid PET;Aβ42;T-tau;P-tau [时效性]