0050 Impact of the Circadian System and Circadian Misalignment on Human Salivary Microbiota

[摘要] IntroductionCircadian rhythm disruption is prevalent in modern society, particularly in night shift workers. Circadian misalignment—the misalignment between the central circadian clock and behavioral/environmental cycles (including sleep/wake, fasting/feeding, dark/light)—results in adverse metabolic effects. Potential underlying mechanisms for these adverse effects include alterations in orogastrointestinal microbiota. However, it remains to be established whether human salivary microbiota have circadian rhythmicity and whether circadian disruption impacts circadian rhythms, community structure, and composition of the microbiota.

[学科分类] 生理学