0112 First Night Effect on Sleep and Heart Rate in Adolescent Boys and Girls: Findings from the NCANDA Study

[摘要] IntroductionWomen are more vulnerable than men to the development of insomnia disorder, with the sex difference emerging during adolescence. Underlying physiological mechanisms are unknown, although upregulation of the autonomic nervous system (ANS) during sleep is strongly implicated in the pathophysiology of insomnia and may be critical in its development in adolescent girls. ANS flexibility is particularly important for adaptive stress responses. The first night in the laboratory is considered a stressful condition and participants who are more sensitive to this effect may be at greater risk for insomnia. Here, we examined possible sex differences in the first night effect on HR and sleep variables in healthy adolescents.

[学科分类] 生理学