0076 NREM Stage 2 Sleep and SWS May Differentially Benefit Episodic Memory

[摘要] IntroductionNon-rapid eye movement (NREM) sleep is known to play a critical role in episodic memory consolidation. Sleep spindles, EEG events in the 9-15 Hz range that are characteristic of NREM stage 2 sleep, are often implicated in this process. However, spindles also occur during slow wave sleep (SWS), and it remains unclear whether stage 2 sleep is sufficient to observe spindle-related memory benefits, if obtaining SWS is necessary as well, or if SWS spindles alone are essential for memory performance. Here, we tested the hypotheses that 1) episodic memory retention would be greater after an afternoon nap, relative to wakefulness, 2) retention would be greater following a nap containing SWS than one without SWS, and 3) spindles during SWS but not stage 2 sleep would predict retention. We also sought to identify whether slow (9-12 Hz) and fast (12-15 Hz) spindles would be differentially associated with memory.

[学科分类] 生理学