0121 Quantitative Anisotropy Within The Default-mode Network Predicts Mood Degradation Following Sleep-deprivation

[摘要] IntroductionSleep deprivation (SD) adversely affects cognition and mood, but some individuals show a trait-like resistance to these effects. The default mode network (DMN), in particular, appears to play a key role in emotional regulation. We hypothesized that individuals with greater white-matter quantitative anisotropy (QA), i.e., greater compactness of white-matter paths, and thicker cortex for regions within the DMN, would demonstrate greater “resistance” to SD with regard to mood degradation across the overnight period without sleep.

[学科分类] 生理学