Insulin: The wrong therapy for type 2 diabetes Lessons learned from a half century of metabolic surgery

[摘要] The biggest gift of metabolic surgery has been its role in sparking a revolutionary sea change in our understanding of type 2 diabetes mellitus (T2DM). Health care professionals have come to recognize that the traditional view of the disease is wrong—T2DM is no longer an unrelenting progressive disease, destined to end in blindness, kidney failure, amputations, and early deaths from heart disease or stroke. Furthermore, the dogma that strict control of glucose levels with insulin will prevent these unfortunate outcomes is also wrong. Instead, durable and full remission of T2DM, with a reduction in other comorbidities and lower mortality, can now be achieved with a metabolic operation that may take only an hour’s duration and a one- or two-day hospital stay.

[学科分类] 外科医学