Predisposing conditions and outcome in adult patients with recurrent pneumococcal meningitis

[摘要] Introduction: Recurrent pneumococcal meningitis is a relatively rare condition associated with predisposing factors. The objective of the study was to evaluate the characteristics and predisposing factors for recurrent pneumococcal meningitis in adults and compare them to patients with non-recurrent meningitis. Methods: A retrospective record review was performed of all patients hospitalized for pneumococcal meningitis in a large tertiary referral center, during a 10-year period. Results: We identified a total of 194 pneumococcal meningitis episodes in 182 patients. Thirty-eight (20%) meningitis episodes in 26 patients were recurrent. Anatomical defects and/or CSF leakage were present in 55% of recurrent pneumococcal meningitis vs. 10% of non-recurrent episodes (p

[学科分类] 神经科学