Plant-based synthesis of silver nanoparticles in Handelia trichophylla and their biological activities

[摘要] In this research, silver nanoparticles (AgNPs) were prepared via a ‘green’ procedure using an aqueous extract of Handelia trichophylla. The formation of AgNPs was confirmed by its light brown colour. The AgNPs were formed in silver nitrate (1 mM) via a bioreduction process in spherically shaped NPs with a mean diameter in the range of 20–50 nm. Moreover, the green synthesized AgNPs seemed to demonstrate a higher antibacterial activity against human pathogenic bacteria. In addition, the in vitro cytotoxicity effect of biosynthesized AgNPs was also investigated, which was detected tobe up to 15.62 $\mu$gml$^{−1}$ in the treated Neuro2A cells. Low toxicity and high antibacterial activity of biosynthesized silvernanoparticles can be utilized in different biological, biomedical and industrial applications.

[学科分类] 材料工程

[关键词] Silver nanoparticles;biosynthesis;Handelia trichophylla;antibacterial;cytotoxicity.