Evidence-based prevention and treatment of osteoporosis after spinal cord injury: a systematic review

[摘要] PurposeSpinal cord injury (SCI) results in accelerated bone mineral density (BMD) loss and disorganization of trabecular bone architecture. The mechanisms underlying post-SCI osteoporosis are complex and different from other types of osteoporosis. Findings of studies investigating efficacy of pharmacological or rehabilitative interventions in SCI-related osteoporosis are controversial. The aim of this study was to review the literature pertaining to prevention and evidence-based treatments of SCI-related osteoporosis.

[学科分类] 骨科学

[关键词] Spinal cord injury;Osteoporosis;Bone loss;Prevention;Treatment