High-throughput flow injection analysis-MRM3 (FIA-MRM3) spectrometry for alternative fast screening of the isomeric methamphetamine and phentermine in blood for forensic toxicology cases in Malaysia

[摘要] Background:Methamphetamine (MA) and phentermine (PTM) are critical isomeric compounds that often coexist in biological specimen in toxicology cases which have similar nominal mass. The dependency of high-resolution mass spectrometer and special chiral stationary phase column for separation of isomeric compound impedes screening throughput especially in meeting high sampling demand.

[学科分类] 医学（综合）

[关键词] MRM3;FIA (flow injection analysis);high-throughput screening;isomeric compounds;methamphetamine;phentermine;WBS;DBS