Differences in Antibodies Against Blood Group, HBV, and Salmonella Regarding Protein Content, Activity, and Affinity in Black and Yellow Healthy Individuals

[摘要] Black and Yellow individuals of various ethnic populations may differ in the immunity to infectious diseases.Our study aimed to explore and compare the detailed production characteristics (protein, activity, and affinity) of antibodies against blood group (natural antibodies), hepatitis B virus (HBV), and Salmonella typhi to find the differences in anti-infectious immunity between Black and Yellow populations.Serum samples of Black and Yellow healthy individuals were collected, diluted in serial dilutions, and several immunological methods were used. Entire antibody features of all antibodies were calculated, according to the results obtained for each dilution.The affinity of natural antibodies, anti-HBs, and S. typhi O antibody was significantly higher among Black individuals than Yellow individuals (P < 0.05). The activity of all antibodies among Blacks was higher than Yellow individuals (P < 0.05). The protein content of all antibodies was significantly higher among Blacks (P < 0.05).Clearly, differences between Black and Yellow individuals for protein, activity, and affinity among different antibodies may lead to exploring the differences in anti-infectious immunity or understanding the incidence of infectious diseases among different races.

[学科分类] 微生物学和免疫学

[关键词] Differences in Antibodies Against Blood Group;HBV;and Salmonella Regarding Protein Content;Activity;and Affinity in Black and Yellow Healthy Individuals;Infectious Diseases;Race;Adaptive Immunity;Antibody Affinity;Ethnic Groups