Steroid Induced Perforation of Meckel’s Diverticulum in an Adult

[摘要] Background: Perforation is one of the rare complications of Meckel’s diverticulum (MD) which carries high morbidity and mortality. Being a congenital variant, complicated MD is usually seen in pediatric population. Case Report: An adult male diagnosed with psoriasis and on systemic steroids for last three months presented with generalized abdominal pain,  and distension. Free fluid and gas in abdomen were detected in erect abdominal X-ray and CT scan. Exploratory laparotomy showed perforated MD. Histopathology report showed presence of ulceration and perforation near ectopic gastric mucosa. The normal diverticular mucosa was ulcerated and perforation was due to persistent low pH inside the diverticulum. Conclusion: High dose systemic steroid therapy may cause spontaneous MD perforation. Detailed history coupled with high degree of clinical and radiological suspicion  is required to clinch the pre-operative diagnosis. 

[学科分类] 生理学

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