Atypical Presentation of Laryngeal Histoplasmosis

[摘要] Background: Medical literature has documented less than 100 cases of histoplasmosis till date. It is an endemic granulomatous fungus disease, which rarely infects the larynx in immunologically competent patients. Case Report: A 68 year old male presented with difficulty in swallowing and progressive change in voice for one month which clinically suggested laryngeal tuberculosis. Laryngoscopy revealed edematous epiglottis and aryepiglottic fold. Histopathological biopsy illustrated sheets of histiocytes with numerous forms of Histoplasma capsulatum. Conclusion: Laryngeal histoplasmosis should be considered in the differential diagnosis of a patient with hoarseness of voice and moreover, in the differential diagnosis of tumors in the vocal folds, causing hoarseness.

[学科分类] 生理学

[关键词] Home page Right