Clinical and Pathological Presentation of Marjolin’s Ulcer as Malignant Peripheral Neural Sheath Tumor

[摘要] Background: The commonest histological presentation of Marjolin’s ulcer is the squamous cell carcinoma. Sarcomas are rare; among the sarcomas, histological diagnosis of a malignant peripheral nerve sheath tumor in a Marjolin’s ulcer is very uncommon. Only one case of Marjolin’s ulcer presenting as a malignant peripheral nerve sheath tumor was found to have been reported in the literature and the patient died after three years of diagnosis without receiving immediate adjuvant therapy because of negative tumor margins. Case Report: We report another case of a patient who has survived ten years without recurrence after a surgical excision with negative tumor margin, post-operative radiotherapy and chemotherapy. Conclusion: Post-operative chemo-radiation therapy prevents recurrence and prolongs survival despite adequate and negative tumor margin.

[学科分类] 生理学

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