High throughput screen for cells with high extracellular metabolite consumption--secretion rates using microfluidic droplets

[摘要] (cont.) After screening the library and analyzing the highest xylose consuming strain, we determined that multiple copies of the xylose isomerase gene was one of the genomic changes responsible for high xylose consumption. This microfluidic screening system is general and has broad applications in strain selection for the overproduction of fuels, chemicals, and pharmaceuticals.

[发布机构] Massachusetts Institute of Technology