Sensitive electrochemical detection of L-cysteine based on a highly stable Pd@Ti3C2Tx (MXene) nanocomposite modified glassy carbon electrode
[摘要] Rapid and real-time detection of L-cysteine (L-Cys) is important for early diagnostics of several diseases and biological disorders. We report here a stable and highly sensitive electrochemical sensor for the detection of L-Cys based on a Pd@Ti3C2Tx (MXene)-modified glassy carbon electrode (GCE). The Pd@Ti3C2Tx nanocomposite was prepared by in situ reduction of Pd(II) salt on the surface of delaminated (DL) Ti3C2Tx nanosheets to form pseudo-spherical palladium nanoparticles (PdNPs) with 2–6 nm size distributions. The MXene acts as the conductive matrix and a reducing agent at the electrode surface, while PdNPs are there to improve the stability of Ti3C2Tx and to enhance the electrocatalytic activity towards L-Cys detection. The Pd@Ti3C2Tx/GCE sensor exhibited a detection limit of 0.14 μM and a linear electro-oxidative response to L-Cys within the concentration range from 0.5 to 10 μM. The sensor also demonstrated excellent selectivity over common interfering ions such as ascorbic acid, uric acid, dopamine and glucose.
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[效力级别] [学科分类] 分析化学
[关键词] [时效性]