First Report of blaCTX-M-28 in Enterobacteriaceae Isolates in the United Arab Emirates

[摘要] Background. The CTX-M family of extended-spectrum beta lactamase (ESBL) enzymes is comprised of over 60gene variants with the predominance ofin many regions. In this report, we present the first description ofin the United Arab Emirates. Methods. Forty-five non-duplicate ESBL producing isolates identified in a secondary care facility in the United Arab Emirates from June to July 2016 were studied. Gene sequencing was performed and DNA sequences were annotated using the BLAST program to identify the gene subtypes. Results. The majority of the ESBL positive isolates were E. coli (; 86.6%) followed by K. pneumoniae () and K. oxytoca (). All isolates harbouredandgenes, 18 had , and 2 werepositive. Thirty-seven isolates (82.2%) were positive for . Othergenes identified include(; isolates #1 and 26) and one each for ,, and . Nowas identified. The predominantsubtype was() followed by one of each of ,, and . Thesubtypes wereand . Conclusion. The findings indicate the first description ofin a setting wherewas previously predominant.

[学科分类] 医学微生物学