Cardiometabolic Changes in Different Gonadal Female States Caused by Mild Hyperuricemia and Exposure to a High-Fructose Diet

[摘要] Background. The objective of this study is to observe if mild hyperuricemia and a high-fructose diet influence the cardiovascular and metabolic systems in hypogonadic female Wistar rats compared to normogonadic female rats. Methods. Fifty-six (56) adult female Wistar rats were used in the present work. Animals were divided into two groups normogonadic (NGN) and hypogonadic (HGN). These groups were also divided into four subgroups in accordance with the treatment control with only water (C), fructose (F), oxonic acid (OA), and fructose 

[学科分类] 内分泌与代谢学