The role of miR-320a and IL-1β in human chondrocyte degradation

[摘要] ObjectivesThis study aimed to explore the role of miR-320a in the pathogenesis of osteoarthritis (OA).MethodsHuman cartilage cells (C28/I2) were transfected with miR-320a or antisense oligonucleotides (ASO)-miR-320a, and treated with IL-1β. Subsequently t

[学科分类] 骨科学

[关键词] Osteoarthritis (OA);microRNA-320a;PBX3;Extracellular matrix;NF-κB