Enhancement of fracture healing in the rat, modulated by compounds that stimulate inducible nitric oxide synthase

[摘要] ObjectivesWe investigated the effects on fracture healing of two up-regulators of inducible nitric oxide synthase (iNOS) in a rat model of an open femoral osteotomy: tadalafil, a phosphodiesterase inhibitor, and the recently reported nutraceutical, COMB-4

[学科分类] 骨科学

[关键词] Inducible nitric oxide synthase;Tadalafil;Fracture;Nutraceutical;Biomechanical