Chondroprotective effects of Salubrinal in a mouse model of osteoarthritis

[摘要] ObjectivesSalubrinal is a synthetic agent that elevates phosphorylation of eukaryotic translation initiation factor 2 alpha (eIF2α) and alleviates stress to the endoplasmic reticulum. Previously, we reported that in chondrocytes, Salubrinal attenuates exp

[学科分类] 骨科学

[关键词] Salubrinal;Osteoarthritis;MMP13;NFkappaB;Cartilage