Effects of a phosphocitrate analogue on osteophyte, subchondral bone advance, and bone marrow lesions in Hartley guinea pigs

[摘要] Objectives The objectives of this study were: 1) to examine osteophyte formation, subchondral bone advance, and bone marrow lesions (BMLs) in osteoarthritis (OA)-prone Hartley guinea pigs; and 2) to assess the disease-modifying activity of an orally admin

[学科分类] 骨科学

[关键词] Osteoarthritis;Subchondral bone;Bone marrow lesions;MMP13;Phosphocitrate