Potential technologies based on stamped periodic nanoparticle array

[摘要] A stamped nanoparticle array patterning technology integrating interference lithography, self assembly and soft lithography is assessed. This technology is capable of parallel patterning of nanoparticles at a large scale. Among several possible applications of this technology, potential for Deoxyribonucleic Acid detection is specifically investigated. Attaching DNA to nanoparticles through a probe molecule changes the local dielectric environment and hence affects surface plasmon resonance. However, the projected plasmon peak shift is not significant. Another detection method is described here to create a visible optical DNA sensor with a tolerable increase in cost relative to existing technologies. Intellectual property issues are also discussed for this technology.

[发布机构] Massachusetts Institute of Technology