Modic (endplate) changes in the lumbar spine: bone micro-architecture and remodelling

[摘要] Abstract Purpose In the literature, inter-vertebral MRI signal intensity changes (Modic changes) were associated with corresponding histological observations on endplate biopsies. However, tissue-level studies were limited. No quantitative histomorphometric study on bone biopsies has yet been conducted for Modic changes. The aim of this study was to characterise the bone micro-architectural parameters and bone remodelling indices associated with Modic changes. Methods Forty patients suffering fr.

[学科分类] 骨科学

[关键词] Modic changes ;Vertebra ;Micro-computed tomography ;Histology ;Micro-architecture ;Bone remodelling