Method validation for the quantification of As, Cd, Hg and Pb in blood by ICP-MS for monitoring purposes

[摘要] Medical laboratories dedicated to the quantification of trace and ultra trace elements in human biological fluids should be accredited according to the ISO standards 15189 : 2007. The use of validated methods for elements determination in blood becomes crucial for laboratories involved in medical analysis. The toxicological importance of As, Cd, Hg and Pb is well known and internationally recognized. These trace elements may be accumulated in human body through the exposure to pollutants in the environment as a result of uncontrolled anthropogenic activities. The internal levels of these elements can be estimated by the collection of blood samples from groups of selected population (biomonitoring)...

[学科分类] 分析化学