Peptidome workflow of serum and urine samples for biomarker discovery

[摘要] Peptidomics plays an important role in clinical proteomics and disease-associated biomarker discovery. It has exhibited mounting potential in early noninvasive diagnosis, prognosis, and treatment evaluation of diseases. This article presents an introduction of peptidomics, the entire peptidomic workflows for serum and urine samples, and a brief overview of recent works in this area. The review is designed to enable researchers to find the most suited strategy for their peptidome studies...

[学科分类] 分析化学