Determination of some banned aromatic amines in waste water using micellar liquid chromatography

[摘要] Aromaticaminesareextensivelyusedinindustrybuttheyareclassifiedasapotentialenvironmentandhealthhazard.Anewhighperformanceliquidchromatographymethodhasbeendevelopedandoptimized,forthedeterminationofeightbannedaromaticamines:benzidine,o-anisidine,o-phenylenediamine,o-nitroaniline,2-methoxy-5-methylaniline(p-cresidine),o-toluidine,p-toluidineandp-chloroaniline.Thechromatographicconditionsusedwere:C18column,0.085MSDS,3.2%(v/v)pentanolmobilephasebufferedatpH7.0,withdetectionat280nm.Undertheseconditions,theeightaromaticamineswereseparatedandquantifiedinindustrialwastewatersinlessthan16min.MethodvalidationstudieswereperformedaccordingtotheICHGuideline.Thepossibilityofdirectinjectionusingmicellarliquidchromatographyreducesthecostandthetotaltimeofanalysis,anddecreaseserrorsourcesowingtominimizedrisksoflossesandchemicalchangesintheanalytes.Theproposedmethodisagoodcandidateforapplicationintheroutineanalysisintheareaofenvironmentalmonitoring...

[学科分类] 分析化学