Crystal structure of 1,3-dihy­droxy-2-(hy­droxy­meth­yl)propan-2-aminium 2-(4-iso­butyl­phen­yl)propano­ate: a simple organic salt of racemic ibuprofen

[摘要] In the title organic salt of ibuprofen with trometamol, C4H12NO3+·C13H17O2−, the carb­oxy­lic acid group of ibuprofen has transferred its proton to the amino N atom of trometamol. In the crystal, the trometamol cations are linked via N—H⋯O hydrogen bonds, forming chains along [001]. To these chains are attached the ibuprofen anions via O—H⋯O and N—H⋯O hydrogen bonds. The chains are linked via further N—H⋯O and O—H⋯O hydrogen bonds, forming sheets parallel to (100). Two C atoms of the propano­ate substituent in the ibuprofen anion are disordered over two sets of sites and were refined with a fixed occupancy ratio of 0.7:0.3.

[学科分类] 数学（综合）

[关键词] CRYSTAL STRUCTURE;IBUPROFEN;TROMETAMOL;MOLECULAR SALT;HYDROGEN BONDING;CHAINS;SHEETS