Donor-Specific HLA Antibody IgG Subclasses Are Associated with Phenotypes of Antibody-Mediated Rejection in Sensitized Renal Allograft Recipients

[摘要] Donor-specific anti–histocompatibility leukocyte antigen antibodies (DSAs) have a strong and frequently considered universally deleterious effect on allografts. Preformed or de novo DSAs activate complement, induce endothelial cell proliferation, and mediate antibody-dependent cellular.

[学科分类] 泌尿医学