Podocyte Expression of B7-1/CD80: Is it a Reliable Biomarker for the Treatment of Proteinuric Kidney Diseases with Abatacept?

[摘要] The story of B7-1 (also known as CD80) and its possible association with nephrotic syndrome began with a chance observation that the gene for B7-1 is overexpressed in podocytes from mice deficient in the α 3 integrin.[1][1] The α 3 β 1 integrin is an important adhesion receptor in podocytes and.

[学科分类] 泌尿医学