Beyond EMT: Epithelial STAT3 as a Central Regulator of Fibrogenesis

[摘要] Studies from early human diabetic kidney disease (DKD) in Pima Indians have suggested that gene targets downstream of signal transduction and activator of transcription 3 (STAT3) are hyperactivated in early disease (initially in the glomerulus and subsequently, in the tubular and interstitial.

[学科分类] 泌尿医学